Signal Transduction Reagents and Kits
Cell Biolabs Inc PhosphoBLOCKER™ Blocking Reagent, 50 g dry blend (1 Liter prepared)
The utilization of anti-phosphoprotein antibodies in western blotting has become a commonly used tool for signal transduction research. Unfortunately, low levels of endogenous phosphoprotein in various cell lysates often can not be detected, even with high concentrations of antibody and long exposure times. Most commercially available western blot blockers (e.g. dry milk, serum) are sufficient to block the unreacted sites on the membrane, reducing the amount of nonspecific antibody binding during the assay; however, they are not designed to preserve phosphoprotein antigens during blotting. Cell Biolabs’ PhosphoBLOCKER™ contains a proprietary formulation that provides several advantages over conventional blockers: (1) It is designed specifically for phosphoprotein blotting; (2) It enhances low level phosphoprotein signal without increasing background; and (3) it is an easy to use premixed dry blend. 50 grams (reconstituted to 1 liter).
Enzo Life Sciences E-64-D, (1mg), CAS Number: 88321-09-9
Calpain and cathepsin inhibitor. Cell-permeable, ethyl ester of E-64-c. The ester is hydrolyzed by intracellular esterases to produce E-64-c. Inhibits calpain and cathepsins B, H, and L. Inhibits degradation of autophagic cargo inside autophagolysosomes. Alternative Name: 2S,3S-trans-(Ethoxycarbonyloxirane-2-carbonyl)-L-leucine-(3-methylbutyl) amide. Aloxistatin. Formula: C17H30N2O5. MW: 342.4. CAS Number: 88321-09-9. Purity: ≥98% (HPLC). Appearance: White solid. Solubility: Soluble in 100% ethanol (>10mg/ml) or DMSO (20mg/ml). Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 2 months. Long Term Storage: -20°C
BPS Bioscience Inc NFAT EGFP REPORTER LENTIVIRUS
The NFAT eGFP Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. BPS BIOSCIENCE INC mfg# 79922
Carnabio Usa Inc CK2A1/B(CSNK2A1/B)/5UG/FULL-LE
CK2a1/b(CSNK2A1/B), Full-length(CK2a1), Wild type, Amino Acid 1-391(CK2a1), 1-215(CK2b), NP_001886.1(CK2a1), NP_001311.3(Ck2b1), Expressed in Insect (sf21); 5microg
Abcam Ascorbic Acid Assay Kit
Ascorbic Acid Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
![Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235713.png-250.jpg)
Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 25MG
Malic enzyme inhibitor ME1 is a small-molecule probe that selectively inhibits the cytosolic NADP+-dependent malic enzyme 1 (ME1) with an in vitro IC50 of 0.15 μM. Supplied as a high-purity solid, it is intended for use in biochemical and cell-based studies to interrogate ME1-dependent metabolic pathways and related cellular phenotypes.
- Potent ME1 inhibition (IC50 0.15 μM).
- High purity (≈99.7%).
- Available in multiple vial sizes for scalability.
- Suitable for biochemical and cell-based assays.
- Supports mechanistic studies of metabolism and disease.
MilliporeSigma BIOLOGY CHEMISCREEN153 MEMB
Life Sciences,Apoptosis & Cell Biology,CHEMISCREEN™ MEMBRANE PREPARATION RECOMBINANT HUMAN u (Mu) OPIOID RECEPTOR
![Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235719.png-250.jpg)
Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 100MG
Malic enzyme inhibitor ME1 is a small-molecule research reagent that potently inhibits cytosolic malic enzyme 1 (ME1) with an IC50 of 0.15 μM. The compound (CAS 522649-59-8) has formula C20H21N3O3, molecular weight 351.4 g/mol, and is supplied as a high-purity powder (≈99.7%) or as a 10 mM solution in DMSO for biochemical and cell-based studies.
- Potent inhibition of ME1 (IC50 0.15 μM).
- High purity suitable for research applications.
- Available as powder and as a 10 mM solution in DMSO.
- Multiple size options including 100 mg for scale-up studies.
- Stable when stored under recommended frozen conditions.
- Applicable to biochemical inhibition assays and cell-based metabolic studies.
Carnabio Usa Inc MRCKA(CDC42BPA)/5UG/TRUNCATED
MRCK(CDC42BPA), Truncated protein, Wild type, Amino Acid 1-574, NP_003598.2, Expressed in Insect (sf21); 5microg
Cell Signaling Technology SignalSlide Phospho-p44/42 MAPK (Thr202/Tyr204) IHC Controls 1 Pack
SignalSlide Phospho-p44/42 MAPK (Thr202/Tyr204) IHC Controls 1 Pack
Echelon Biosciences Research Labs EICOSANOYL LPA 1 mg
Arachidoyl LPA, 20:0 LPA (aka Eicosanoyl LPA) is an analog of lysophosphatidic acid (LPA), a lysophospholipid involved in cell proliferation. Lysophosphatidic Acid (LPA) is a small lysophospholipid involved in diverse cellular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogenesis, tumor invasion, and smooth muscle contraction. LPA binds to several G-coupled protein receptors to initiate its biological functions. In cancer, LPA primarily promotes cell survival, migration and invasion. May contain up to 5-10% of the 2-acyl isomer due to acyl transfer. This item is non returnable